How do anti-wrinkle injections stop sweating? | Cityskin Cosmetic Clinic

Sweating is one of your body’s ways to reduce its’ temperature. Sweating cools down the body by evaporation which draws heat away from the body thereby reducing your temperature.

Excessive sweating (hyperhidrosis) is more common than previously thought – with 1:20 people in a recent USA study reporting symptoms1 of excessive sweating. Interestingly only half of patients with hyperhidrosis discuss their symptoms with a health care professional1 which means that there are a lot of people in the population going untreated.

Anti-wrinkle injections are an effective way of treating sweating and we are going to explain how the treatment works.

How do we sweat?

The image below shows a simplified illustration of how we sweat. When our body warms up (e.g through exercise or fever) or when we experience a ‘fight or flight’ event such as running from a dog the brain sends a signal down the nerve telling the nerve ending to release a chemical called acetylcholine (Ach).

Acetylcholine is a chemical messenger which tells the sweat glands to start producing sweat. Your body then produces sweat at the correct rate to cool the body down. When the body is back to its’ normal temperature or when you have stopped running from that dog the brain stops sending signals to release Ach and you stop sweating.

hyperhidrosis treatment

How do anti-wrinkle injections reduce sweating?

Anti-wrinkle injections can injected superficially under the skin to reduce sweating. The diagram below show what happens after anti-wrinkle injections have been injected. Note that this effect only affects a 1cm diameter around the anti-wrinkle injection point. This time when the body warms up or you experience a stressful event the brain still sends a signal down the nerve but the anti-wrinkle product blocks the release of Acetylcholine around the area that has been injected. This prevents the sweat receptors receiving the signal to release sweat and as a result you sweat less.

Which areas of the body can be treated with anti-wrinkle injections to reduce sweating?

Common areas that we treat include:

Hands and feet can also be treated with anti-wrinkle injections but we do not offer this at Cityskin.

Affected by excess sweating? Contact us to see if we can help

If excess sweating is something that affects you and you would like advice please get in touch with the Cityskin team who are more than happy to help point you in the right direction.


1. Arch Dermatol Res. 2016; 308(10): 743–749

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